MEK2 anticorps (AA 1-400)

N° du produit ABIN7869312

L’anticorps anti-MEK2 Monoclonal Souris est utilisé pour la détection de MEK2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour MEK2 anticorps (AA 1-400) (ABIN7869312)

Antigène: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MEK2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2B4

Détail du produit anti-MEK2 anticorps

Épitope: AA 1-400

Fonction: MEK2 Antibody / MAP2K2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M1-V400) was used as the immunogen for the MEK2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the MEK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MEK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MEK2

Antigène: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Autre désignation: MEK2

Sujet: Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2), also called PRKMK2 or MEK2, is an enzyme that in humans is encoded by the MAP2K2 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MAP2K2 is mapped to 19p13.3. This kinase is known to play a critical role in mitogen growth factor signal transduction, and the inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax. Recombinant MEK2 and MEK1 both could activate human ERK1 in vitro, and they further characterized biochemically the 2 MAP2Ks. MAP2K2 has been shown to interact with MAPK3 and ARAF.

UniProt: P36507

Pathways: Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling