PKC epsilon anticorps (AA 1-690)

N° du produit ABIN7869528

L’anticorps anti-PKC epsilon Polyclonal Lapin est utilisé pour la détection de PKC epsilon dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour PKC epsilon anticorps (AA 1-690) (ABIN7869528)

Antigène: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC epsilon est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PKC epsilon anticorps

Épitope: AA 1-690

Fonction: PKCE Antibody / PKC epsilon / PRKCE

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids M1-K690) was used as the immunogen for the PKCE antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PKCE antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PKCE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PKC epsilon

Antigène: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Autre désignation: PKCE

Sujet: Protein kinase C epsilon type, also known as PKCE, is an enzyme that in humans is encoded by the PRKCE gene. The protein encoded by this gene is one of the PKC family members. PRKCE is mapped to 2p21. This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. It has been found that activation of PRKCE can induce VR1 channel activity at room temperature in the absence of any other agonist. PRKCE gene plays a role in apoptosis signaling pathways in thyroid cells and it has been indicated that a naturally occurring PRKCE mutant that functions as a dominant negative can block cell death triggered by a variety of stimuli. Expression of PRKCE inhibits chemotherapy-induced caspase-3 activation and apoptosis, thereby leading to cell survival.

UniProt: Q02156

Pathways: TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling