VPS4A anticorps (AA 1-71)

N° du produit ABIN7869533

Cet anticorps Lapin Polyclonal détecte spécifiquement VPS4A dans WB, ELISA, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour VPS4A anticorps (AA 1-71) (ABIN7869533)

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS4A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-VPS4A anticorps

Épitope: AA 1-71

Fonction: VPS4A Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-K71) was used as the immunogen for the VPS4A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the VPS4A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the VPS4A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur VPS4A

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Autre désignation: VPS4A

Sujet: Vacuolar protein sorting-associated protein 4A is a protein that in humans is encoded by the VPS4A gene. It is mapped to 16q22.1. The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18.

UniProt: Q9UN37

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events