FOLR2 anticorps (AA 18-46)
Aperçu rapide pour FOLR2 anticorps (AA 18-46) (ABIN7871424)
Antigène
Voir toutes FOLR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 18-46
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Fonction
- FOLR2 Antibody / Folate Receptor beta
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 18-46 from the human protein were used as the immunogen for the FOLR2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the FOLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the FOLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
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Autre désignation
- FOLR2
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Sujet
- FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
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UniProt
- P14207
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Pathways
- Dicarboxylic Acid Transport
Antigène
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