IFI16 anticorps (AA 183-743)

N° du produit ABIN7871472

L’anticorps anti-IFI16 Monoclonal Souris est utilisé pour la détection de IFI16 dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour IFI16 anticorps (AA 183-743) (ABIN7871472)

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFI16 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2I3D7

Détail du produit anti-IFI16 anticorps

Épitope: AA 183-743

Fonction: IFI16 Antibody / Gamma-interferon-inducible protein 16

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E183-K743) was used as the immunogen for the IFI16 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the IFI16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the IFI16 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IFI16

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Autre désignation: IFI16

Sujet: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome