MEK2 anticorps (AA 200-229)
Aperçu rapide pour MEK2 anticorps (AA 200-229) (ABIN7871893)
Antigène
Voir toutes MEK2 (MAP2K2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 200-229
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Fonction
- MAP2K2 Antibody / MEK2
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 200-229 from the human protein was used as the immunogen for the MAP2K2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the MAP2K2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the MAP2K2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
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Autre désignation
- MAP2K2
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Sujet
- MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
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UniProt
- P36507
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Pathways
- Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Antigène
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