Neuregulin 1 anticorps (AA 21-242)

N° du produit ABIN7872153

L’anticorps anti-Neuregulin 1 Monoclonal Souris est utilisé pour la détection de Neuregulin 1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Neuregulin 1 anticorps (AA 21-242) (ABIN7872153)

Antigène: Neuregulin 1 (NRG1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuregulin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HRGA1-1

Détail du produit anti-Neuregulin 1 anticorps

Épitope: AA 21-242

Fonction: NRG1 Antibody / Neuregulin-1

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the NRG1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the NRG1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the NRG1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Neuregulin 1

Antigène: Neuregulin 1 (NRG1)

Autre désignation: NRG1

Sujet: Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

UniProt: Q02297

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation