MR1 anticorps (AA 23-269)

N° du produit ABIN7872521

Cet anticorps Lapin Polyclonal détecte spécifiquement MR1 dans ELISA, WB et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MR1 anticorps (AA 23-269) (ABIN7872521)

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MR1 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-MR1 anticorps

Épitope: AA 23-269

Fonction: MR1 Antibody / MHC class I related protein 1

Purification: Antigen affinity purified

Immunogène: Amino acids R23-D269 from the human protein were used as the immunogen for the MR1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MR1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MR1

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Autre désignation: MR1

Sujet: Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints