Cet anticorps anti-PKC theta Polyclonal Lapin (ABIN7872553) détecte spécifiquement PKC theta dans WB, ELISA et IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
PRKCQ
Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Singe
WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the PKC theta antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the PKC theta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Protein kinase C theta is an enzyme that in humans is encoded by the PRKCQ gene. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.