FOXO3 anticorps (AA 312-537)
Aperçu rapide pour FOXO3 anticorps (AA 312-537) (ABIN7873851)
Antigène
Voir toutes FOXO3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 312-537
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Fonction
- FKHRL1 Antibody / FOXO3A
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids R312-Q537) was used as the immunogen for the FKHRL1 antibody.
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Isotype
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 Reactivité: Humain WB, IHC, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 Reactivité: Humain, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 Reactivité: Humain WB, IF, IHC (p), ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Mouton, Lapin, Cobaye, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 Reactivité: Humain, Rat WB, IHC, IF, ICC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivité: Humain ELISA, IF, IHC (p) Hôte: Souris Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivité: Humain WB, ELISA, IF, IHC (p) Hôte: Souris Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Monoclonal 1E2 unconjugated Recombinant Antibody
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Indications d'application
- Optimal dilution of the FKHRL1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the FKHRL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Autre désignation
- FKHRL1
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Sujet
- Forkhead box O3, also known as FKHRL1 (Forkhead in rhabdomyosarcoma-like 1) or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
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UniProt
- O43524
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Pathways
- Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Antigène
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