SPHK1 anticorps (AA 55-357)

N° du produit ABIN7875687

L’anticorps anti-SPHK1 Polyclonal Lapin est utilisé pour la détection de SPHK1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour SPHK1 anticorps (AA 55-357) (ABIN7875687)

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-SPHK1 anticorps

Épitope: AA 55-357

Fonction: Sphingosine kinase 1 Antibody / SPHK1

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E55-N357) was used as the immunogen for the Sphingosine kinase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Sphingosine kinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Sphingosine kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SPHK1

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Autre désignation: Sphingosine kinase 1

Sujet: SPHK1 (Sphingosine Kinase 1), is an enzyme that in humans is encoded by the SPHK1 gene. Melendez et al.(2000) mapped the SPHK1 gene to chromosome 17q25.2 based on sequence identity with ESTs mapped to this region. Kohama et al.(1998) demonstrated that recombinant mouse Sphk1 can specifically phosphorylate D-erythro-sphingosine and that D, L-threo-dihydrosphingosine and N, N-dimethylsphingosine can act as competitive inhibitors of recombinant Sphk1. Pitson et al.(2000) found that recombinant SPHK1 and endogenous SPHK1 purified from placenta had identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties.

UniProt: Q9NYA1

Pathways: VEGF Signaling