RASGRP2 anticorps (AA 7-34)
Aperçu rapide pour RASGRP2 anticorps (AA 7-34) (ABIN7876487)
Antigène
Voir toutes RASGRP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 7-34
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Fonction
- CalDAG-GEFI Antibody / RASGRP2
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 7-34 from the human protein was used as the immunogen for the CalDAG-GEFI antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the CalDAG-GEFI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the CalDAG-GEFI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
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Autre désignation
- CalDAG-GEFI
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Sujet
- The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
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UniProt
- Q7LDG7
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Pathways
- TCR Signaling
Antigène
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