PDK4 anticorps (AA 85-129)

N° du produit ABIN7876971

L’anticorps anti-PDK4 Polyclonal Lapin est utilisé pour la détection de PDK4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour PDK4 anticorps (AA 85-129) (ABIN7876971)

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-PDK4 anticorps

Épitope: AA 85-129

Fonction: Pyruvate dehydrogenase kinase 4 Antibody / PDK4

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids V85-N129) was used as the immunogen for the Pyruvate dehydrogenase kinase 4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Pyruvate dehydrogenase kinase 4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Pyruvate dehydrogenase kinase 4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PDK4

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Autre désignation: Pyruvate dehydrogenase kinase 4

Sujet: Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial (PDK4) is an enzyme that in humans is encoded by the PDK4 gene. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

UniProt: Q16654

Pathways: Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg