Prothrombin anticorps (AA 97-124)
Aperçu rapide pour Prothrombin anticorps (AA 97-124) (ABIN7877259)
Antigène
Voir toutes Prothrombin (F2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 97-124
-
Fonction
- Prothrombin Antibody
-
Purification
- Antigen affinity purified
-
Immunogène
- Recombinant human protein (amino acids Y97-R124) was used as the immunogen for the Prothrombin antibody.
-
Isotype
- IgG2b
-
-
-
-
Indications d'application
- Optimal dilution of the Prothrombin antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the Prothrombin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
-
Autre désignation
- Prothrombin
-
Sujet
- F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.
-
UniProt
- P00734
-
Pathways
- Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
-