EIF2C3 anticorps (full length)

N° du produit ABIN7878208

Cet anticorps anti-EIF2C3 Monoclonal Souris (Clone PCRP-AGO3-1C5) (ABIN7878208) détecte spécifiquement EIF2C3 dans ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EIF2C3 anticorps (full length) (ABIN7878208)

Antigène: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF2C3 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-AGO3-1C5

Détail du produit anti-EIF2C3 anticorps

Épitope: full length

Fonction: AGO3 Antibody / Argonaute-3 / eIF2C3

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human AGO3 protein was used as the immunogen for the AGO3 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the AGO3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the AGO3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur EIF2C3

Antigène: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Autre désignation: AGO3

Sujet: This antigen is involved in binding and translation repression of short RNAs. This antigen is also known as Argonaute RISC catalytic component 3. Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5-flanking sequences to the region of guide-target complementarity.

UniProt: Q9H9G7

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway