Angiotensin I Converting Enzyme 1 anticorps
Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (ABIN7879972)
Antigène
Voir toutes Angiotensin I Converting Enzyme 1 (ACE) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- ACE Antibody / Angiotensin-Converting Enzyme
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Purification
- Affinity purified
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Immunogène
- A synthetic peptide specific to human Angiotensin-Converting Enzyme was used as the immunogen for the ACE antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the ACE antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store the ACE antibody at -20oC.
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- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
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Autre désignation
- ACE
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Sujet
- The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [RefSeq]
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UniProt
- P12821
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
Antigène
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