Recombinant CD247 anticorps

N° du produit ABIN7880264

Cet anticorps Lapin Monoclonal détecte spécifiquement CD247 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD247 anticorps (ABIN7880264)

Antigène: CD247 (CD247 Molecule (CD247))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD247 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IHI-3

Détail du produit anti-CD247 anticorps

Fonction: CD247 Antibody / CD3 zeta

Purification: Affinity chromatography

Immunogène: A peptide sequence specific to CD3 zeta protein was used as the immunogen for the CD247 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CD247 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CD247 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD247

Antigène: CD247 (CD247 Molecule (CD247))

Autre désignation: CD247

Sujet: CD247 (CD3 zeta) is a key signaling component of the T cell receptor (TCR) complex, essential for antigen recognition and T cell activation. It contains multiple immunoreceptor tyrosine-based activation motifs (ITAMs) that initiate downstream signaling cascades upon antigen engagement, leading to T cell proliferation and differentiation.

CD247 is predominantly expressed in T cells and natural killer (NK) cells, where it regulates immune responses against pathogens and abnormal cells. Alterations in CD247 expression or function have been linked to immunodeficiencies, autoimmune diseases, and cancer, making it a valuable focus for immunological research.

Using a high-quality CD247 antibody enables precise detection in applications such as western blot, flow cytometry, and immunohistochemistry. A CD247 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in T cell biology, immune signaling, and disease pathogenesis. Selecting the right CD247 antibody is essential for producing accurate and consistent research results.

UniProt: P20963

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway