Recombinant LAT anticorps

N° du produit ABIN7881473

Cet anticorps anti-LAT Monoclonal Lapin (Clone 28L72) (ABIN7881473) détecte spécifiquement LAT dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant LAT anticorps (ABIN7881473)

Antigène: LAT (Linker For Activation of T Cells (LAT))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LAT est non-conjugé

Application: Western Blotting (WB)

Clone: 28L72

Détail du produit anti-LAT anticorps

Fonction: LAT Antibody / Linker for Activation of T cells

Purification: Affinity chromatography

Immunogène: A synthetic peptide from human LAT protein was used as the immunogen for the LAT antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LAT antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the LAT antibody at -20oC.

Détails sur LAT

Antigène: LAT (Linker For Activation of T Cells (LAT))

Autre désignation: LAT

Sujet: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. [UniProt]

UniProt: O43561

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway