PPARA anticorps

N° du produit ABIN7881919

L’anticorps anti-PPARA Monoclonal Souris est utilisé pour la détection de PPARA dans des échantillons de Humain et Souris. Il a été validé pour WB, FACS, IF et IHC (p).

Aperçu rapide pour PPARA anticorps (ABIN7881919)

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARA est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1331CT894-186-143

Détail du produit anti-PPARA anticorps

Fonction: PPARA Antibody / PPAR alpha

Purification: Protein G affinity

Immunogène: A recombinant human protein was used as the immunogen for the PPARA antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the PPARA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PPARA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PPARA

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Autre désignation: PPARA

Sujet: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C