Serotonin Receptor 1A anticorps (3rd Intracellular Loop)

N° du produit ABIN7885388

Cet anticorps anti-Serotonin Receptor 1A Polyclonal Lapin (ABIN7885388) détecte spécifiquement Serotonin Receptor 1A dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour Serotonin Receptor 1A anticorps (3rd Intracellular Loop) (ABIN7885388)

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Classe de qualité: Carrier-free

Détail du produit anti-Serotonin Receptor 1A anticorps

Épitope: 3rd Intracellular Loop, AA 251-266

Fonction: A Rabbit Polyclonal Antibody to 5-Hydroxytryptamine Receptor 1A

Homologie: Mouse - identical

Purification: Affinity purified on immobilized antigen.

Immunogène: KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine receptor 1A

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:100

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7236780)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: 5-Hydroxytryptamine receptor 1A

Sujet:

Synonyms: 5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A

Description: Serotonin (5-hydroxytryptamine, 5-HT1) is an important neurotransmitter in the central nervous system (CNS) that exerts its neuronal activity via 5-HT receptors.5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-protein coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels.2The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F) which share 41-63 % overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the CNS, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3 Activation of 5-HT1A receptor decreases blood pressure and heart rate, and is involved in learning, memory, relieving anxiety and depression.1,4

ID gène: 24473

UniProt: P19327

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour