SGK1 anticorps (pSer422)
Aperçu rapide pour SGK1 anticorps (pSer422) (ABIN745703)
Antigène
Voir toutes SGK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer422
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser422
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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Autre désignation
- SGK1
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Sujet
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Synonyms: SGK, Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, SGK1
Background: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
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ID gène
- 6446
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UniProt
- O00141
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Pathways
- Signalisation MAPK, Signalisation Notch, Steroid Hormone Mediated Signaling Pathway
Antigène
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