PTK2B anticorps (pTyr881)

N° du produit ABIN745778

L’anticorps anti-PTK2B Polyclonal Lapin est utilisé pour la détection de PTK2B dans des échantillons de Souris et Rat. Il a été validé pour WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro).

Aperçu rapide pour PTK2B anticorps (pTyr881) (ABIN745778)

Antigène: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PTK2B anticorps

Épitope: pTyr881

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Pyk2 around the phosphorylation site of Tyr881

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PTK2B

Antigène: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Autre désignation: Pyk2

Sujet:

Synonyms: CADTK, CAK beta , CAKB antibody, CAKbeta, Calcium dependent tyrosine kinase, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, E430023O05Rik, EC 2.7.10.2, FADK 2, FADK2, FAK 2, FAK1, FAK2, Focal Adhesion Kinase 2, MGC124628, PKB, pp125FAK, Proline Rich Tyrosine Kinase 2, Proline-rich tyrosine kinase 2, Protein kinase B, Protein Tyrosine Kinase 2 Beta, PTK 2B, PTK antibody PTK2B, PTK2B protein tyrosine kinase 2 beta, PYK 2, PYK2, RAFTK, Related adhesion focal tyrosine kinase.

Background: PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.

ID gène: 2185

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling