APOB anticorps (AA 246-450) (Cy3)

N° du produit ABIN7969346

Cet anticorps anti-APOB Polyclonal Lapin conjugué à Cy3 (ABIN7969346) détecte spécifiquement APOB dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour APOB anticorps (AA 246-450) (Cy3) (ABIN7969346)

Antigène: APOB (Apolipoprotein B (APOB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOB est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-APOB anticorps (Cy3)

Épitope: AA 246-450

Fonction: Anti-Apolipoprotein B/APOB Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450). Human Apolipoprotein B shares 82.4%,80.5% amino acid (aa) sequence identity with mouse,rat Apolipoprotein B,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450). Human Apolipoprotein B shares 82.4% and 80.5% amino acid (aa) sequence identity with mouse and rat Apolipoprotein B, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur APOB

Antigène: APOB (Apolipoprotein B (APOB))

Autre désignation: APOB

Sujet:

Background: Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Gene Full Name: apolipoprotein B

ID gène: 338

UniProt: P04114

Pathways: Lipid Metabolism