Prothrombin anticorps (AA 97-124) (HRP)

N° du produit ABIN7980693

Cet anticorps Souris Monoclonal détecte spécifiquement Prothrombin dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Prothrombin anticorps (AA 97-124) (HRP) (ABIN7980693)

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prothrombin est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 5B6G1

Détail du produit anti-Prothrombin anticorps (HRP)

Épitope: AA 97-124

Fonction: Anti-Prothrombin Antibody (monoclonal, 5B6G1) HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Prothrombin recombinant protein (Position: Y97-R124).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: F2

Sujet:

Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

Gene Full Name: coagulation factor II, thrombin

ID gène: 2147

UniProt: P00734

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling