Prothrombin anticorps (C-Term) (Fluoro488)

N° du produit ABIN7980700

L’anticorps anti-Prothrombin Polyclonal Lapin est utilisé pour la détection de Prothrombin dans des échantillons de Rat. Il a été validé pour FACS.

Aperçu rapide pour Prothrombin anticorps (C-Term) (Fluoro488) (ABIN7980700)

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prothrombin est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-Prothrombin anticorps (Fluoro488)

Épitope: C-Term

Fonction: Anti-Prothrombin/F2 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: F2

Sujet:

Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al. (1987) assigned the gene for human prothrombin (F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

Gene Full Name: coagulation factor II(thrombin)

Sequence Similarities: Belongs to the peptidase S1 family.

ID gène: 29251

UniProt: P18292

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling