Prothrombin anticorps (C-Term)
Aperçu rapide pour Prothrombin anticorps (C-Term) (ABIN7980708)
Antigène
Voir toutes Prothrombin (F2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Épitope
- C-Term
-
Fonction
- Anti-Prothrombin/F2 Antibody
-
Specificité
- No cross reactivity with other proteins.
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins
-
Attributs du produit
- Anti-Prothrombin/F2 Antibody. Tested in WB applications. This antibody reacts with Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.1-0.5 μg/mL, Rat
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
-
Précaution d'utilisation
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
-
-
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
-
Autre désignation
- F2
-
Sujet
-
Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al. (1987) assigned the gene for human prothrombin (F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.
Gene Full Name: coagulation factor II(thrombin)
Sequence Similarities: Belongs to the peptidase S1 family.
-
Poids moléculaire
- 100 kDa
-
ID gène
- 29251
-
UniProt
- P18292
-
Pathways
- Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
-