Cullin 2 anticorps (AA 389-745)
Aperçu rapide pour Cullin 2 anticorps (AA 389-745) (ABIN7982009)
Antigène
Voir toutes Cullin 2 (CUL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 389-745
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Fonction
- Anti-CUL2 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-CUL2 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived human CUL2 recombinant protein (Position: E389-A745).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL Flow Cytometry(Fixed), 1-3 μg/1x106 cells ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Cullin 2 (CUL2)
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Autre désignation
- CUL2
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Sujet
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Background: Cullin 2 (CUL2) is a protein that in humans is encoded by the CUL2 gene. Using immunofluorescence, it is showed that CUL2 is a cytosolic protein that can be translocated to the nucleus by VHL. By fluorescence in situ hybridization, this gene is mapped to 10p11.2-p11.1, a region reported to show loss of heterozygosity (LOH) in several forms of human cancer, including non-clear cell renal cell carcinoma. CUL2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Gene Full Name: cullin 2
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Poids moléculaire
- 87 kDa
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ID gène
- 8453
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UniProt
- Q13617
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Pathways
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
Antigène
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