FGF19 anticorps (Middle Region) (Fluoro488)

N° du produit ABIN7990479

Cet anticorps Lapin Polyclonal détecte spécifiquement FGF19 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FGF19 anticorps (Middle Region) (Fluoro488) (ABIN7990479)

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF19 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-FGF19 anticorps (Fluoro488)

Épitope: Middle Region

Fonction: Anti-Fibroblast growth factor 19 FGF19 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human FGF19.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur FGF19

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Autre désignation: FGF19

Sujet:

Background: FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity.

Gene Full Name: fibroblast growth factor 19

ID gène: 9965

UniProt: O95750

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway