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FOXO3 anticorps (AA 312-537) (Cy3)

L’anticorps anti-FOXO3 Polyclonal Lapin est utilisé pour la détection de FOXO3 dans des échantillons de Humain. Il a été validé pour FACS.
N° du produit ABIN7991536
720,50 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 8 à 12 jours ouvrables

Aperçu rapide pour FOXO3 anticorps (AA 312-537) (Cy3) (ABIN7991536)

Antigène

Voir toutes FOXO3 Anticorps
FOXO3 (Forkhead Box O3 (FOXO3))

Reactivité

  • 195
  • 112
  • 107
  • 9
  • 7
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Humain

Hôte

  • 192
  • 5
  • 1
Lapin

Clonalité

  • 134
  • 64
Polyclonal

Conjugué

  • 89
  • 13
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp FOXO3 est conjugé à/à la Cy3

Application

  • 148
  • 84
  • 62
  • 56
  • 46
  • 34
  • 21
  • 15
  • 15
  • 14
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • Épitope

    • 50
    • 13
    • 12
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 312-537

    Fonction

    Anti-FOXO3A/FOXO3 Antibody Cy3 Conjugated

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human FOXO3A/FOXO3 recombinant protein (Position: R312-Q537).

    Isotype

    IgG
  • Indications d'application

    Flow Cytometry, 1-3 μg/1x106 cells

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    Date de péremption

    12 months
  • Antigène

    FOXO3 (Forkhead Box O3 (FOXO3))

    Autre désignation

    FOXO3

    Sujet

    Background: Forkhead box O3, also known as FKHRL1 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.

    Gene Full Name: forkhead box O3

    ID gène

    2309

    UniProt

    O43524

    Pathways

    Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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