GADD45A anticorps (C-Term) (HRP)

N° du produit ABIN7995180

Cet anticorps Lapin Polyclonal détecte spécifiquement GADD45A dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GADD45A anticorps (C-Term) (HRP) (ABIN7995180)

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45A est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GADD45A anticorps (HRP)

Épitope: C-Term

Fonction: Anti-GADD45A Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human GADD45A, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GADD45A

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Autre désignation: GADD45A

Sujet:

Background: Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. It is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. In addition, Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

Gene Full Name: growth arrest and DNA damage inducible alpha

ID gène: 1647

UniProt: P24522

Pathways: Signalisation p53, Cycle Cellulaire