IL15RA anticorps (AA 31-174) (HRP)

N° du produit ABIN8001920

Cet anticorps Lapin Polyclonal détecte spécifiquement IL15RA dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour IL15RA anticorps (AA 31-174) (HRP) (ABIN8001920)

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL15RA est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-IL15RA anticorps (HRP)

Épitope: AA 31-174

Fonction: Anti-IL15RA Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human IL15RA recombinant protein (Position: I31-T174).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IL15RA

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Autre désignation: IL15RA

Sujet:

Background: Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Gene Full Name: interleukin 15 receptor subunit alpha

ID gène: 3601

UniProt: Q13261

Pathways: Signalistation JAK/STAT