IL-8 anticorps (AA 23-99) (Cy3)

N° du produit ABIN8002872

L’anticorps anti-IL-8 Polyclonal Lapin est utilisé pour la détection de IL-8 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour IL-8 anticorps (AA 23-99) (Cy3) (ABIN8002872)

Antigène: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-8 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-IL-8 anticorps (Cy3)

Épitope: AA 23-99

Fonction: Anti-IL8/CXCL8 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human IL-8 recombinant protein (Position: A23-S99).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL-8

Antigène: IL-8 (IL8) (Interleukin 8 (IL8))

Autre désignation: CXCL8

Sujet:

Background: Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. Interleukin-8 (IL8) is a member of the CXC chemokine family. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. The genes for IL8 have been co-localized on a 335-kb genomic fragment.

Gene Full Name: C-X-C motif chemokine ligand 8

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

ID gène: 3576

UniProt: P10145

Pathways: Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy