JAK3 anticorps (AA 406-661) (FITC)

N° du produit ABIN8003602

Cet anticorps anti-JAK3 Polyclonal Lapin conjugué à FITC (ABIN8003602) détecte spécifiquement JAK3 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour JAK3 anticorps (AA 406-661) (FITC) (ABIN8003602)

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK3 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-JAK3 anticorps (FITC)

Épitope: AA 406-661

Fonction: Anti-JAK3 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human JAK3 recombinant protein (Position: Q406-D661).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur JAK3

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Autre désignation: JAK3

Sujet:

Background: Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene. It is mapped to 19p13.11. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Gene Full Name: Janus kinase 3

ID gène: 3718

UniProt: P52333

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response