Kallikrein 5 anticorps (C-Term) (FITC)

N° du produit ABIN8003888

Cet anticorps Lapin Polyclonal détecte spécifiquement Kallikrein 5 dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour Kallikrein 5 anticorps (C-Term) (FITC) (ABIN8003888)

Antigène: Kallikrein 5 (KLK5)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 5 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-Kallikrein 5 anticorps (FITC)

Épitope: C-Term

Fonction: Anti-Kallikrein 5/KLK5 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5, different from the related rat sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Kallikrein 5

Antigène: Kallikrein 5 (KLK5)

Autre désignation: KLK5

Sujet:

Background: KLK5 (Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme (SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.

Gene Full Name: kallikrein related-peptidase 5

Sequence Similarities: Belongs to the integrin beta chain family.

ID gène: 68668

UniProt: Q9D140

Pathways: Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling