GNB3 anticorps (AA 81-180)

N° du produit ABIN751498

Détail du produit anti-GNB3 anticorps

Antigène: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Épitope: AA 81-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNB3 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human G protein beta 3

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur GNB3

Antigène: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Autre désignation: G protein beta 3/GNB3 (GNB3 Produits)

Synonymes: anticorps Gnb-3, anticorps MGC68913, anticorps MGC130764, anticorps gnb3, anticorps zgc:73058, anticorps zgc:77780, anticorps wu:fk54b04, anticorps gnb3l, anticorps zgc:92641, anticorps G protein subunit beta 3, anticorps guanine nucleotide binding protein (G protein), beta 3, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3b, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3a, anticorps GNB3, anticorps Gnb3, anticorps gnb3.S, anticorps gnb3b, anticorps gnb3a

Sujet:

Synonyms: Gnb3, Guanine nucleotide binding protein G protein, beta polypeptide 3, Guanine nucleotide binding protein G, Hypertension associated protein, IG, SG, Transducin beta chain 3, Tsubunit beta 3, GBB3_HUMAN.

Background: G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.

ID gène: 2784

Pathways: Peptide Hormone Metabolism, Myometrial Relaxation and Contraction