NLRP6 anticorps (AA 14-887) (APC)

N° du produit ABIN8015919

L’anticorps anti-NLRP6 Polyclonal Lapin est utilisé pour la détection de NLRP6 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour NLRP6 anticorps (AA 14-887) (APC) (ABIN8015919)

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-NLRP6 anticorps (APC)

Épitope: AA 14-887

Fonction: Anti-NLRP6 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human NLRP6 shares 71.7%,72.9% amino acid (aa) sequence identity with mouse,rat NLRP6,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NLRP6 recombinant protein (Position: R14-E887). Human NLRP6 shares 71.7% and 72.9% amino acid (aa) sequence identity with mouse and rat NLRP6, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NLRP6

Sujet:

Background: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: NLR family pyrin domain containing 6

ID gène: 171389

UniProt: P59044

Pathways: Inflammasome