NLRP6 anticorps (AA 14-887)

N° du produit ABIN8015922

L’anticorps anti-NLRP6 Polyclonal Lapin est utilisé pour la détection de NLRP6 dans des échantillons de Humain. Il a été validé pour ELISA, WB et FACS.

Aperçu rapide pour NLRP6 anticorps (AA 14-887) (ABIN8015922)

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-NLRP6 anticorps

Épitope: AA 14-887

Fonction: Anti-NLRP6 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human NLRP6 shares 71.7%,72.9% amino acid (aa) sequence identity with mouse,rat NLRP6,respectively.

Attributs du produit: Anti-NLRP6 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NLRP6 recombinant protein (Position: R14-E887). Human NLRP6 shares 71.7% and 72.9% amino acid (aa) sequence identity with mouse and rat NLRP6, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NLRP6

Sujet:

Background: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: NLR family pyrin domain containing 6

Poids moléculaire: 105 kDa

ID gène: 171389

UniProt: P59044

Pathways: Inflammasome