Phospholipase C gamma 2 anticorps (AA 1201-1258) (HRP)

N° du produit ABIN8022142

Cet anticorps anti-Phospholipase C gamma 2 Polyclonal Lapin conjugué à HRP (ABIN8022142) détecte spécifiquement Phospholipase C gamma 2 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Phospholipase C gamma 2 anticorps (AA 1201-1258) (HRP) (ABIN8022142)

Antigène: Phospholipase C gamma 2 (PLCG2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholipase C gamma 2 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Phospholipase C gamma 2 anticorps (HRP)

Épitope: AA 1201-1258

Fonction: Anti-PLCG 2/PLCG2 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human PLCG 2 recombinant protein (Position: R1201-V1258).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Phospholipase C gamma 2

Antigène: Phospholipase C gamma 2 (PLCG2)

Autre désignation: PLCG2

Sujet:

Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Gene Full Name: phospholipase C gamma 2

ID gène: 5336

UniProt: P16885

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling