PIAS3 anticorps (N-Term) (PE)

N° du produit ABIN8027319

L’anticorps anti-PIAS3 Polyclonal Lapin est utilisé pour la détection de PIAS3 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour PIAS3 anticorps (N-Term) (PE) (ABIN8027319)

Antigène: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS3 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-PIAS3 anticorps (PE)

Épitope: N-Term

Fonction: Anti-PIAS3 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human PIAS3, which shares 97.6% amino acid (aa) sequence identity with both mouse and rat PIAS3.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PIAS3

Antigène: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Autre désignation: PIAS3

Sujet:

Background: E3 SUMO-protein ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It ly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Gene Full Name: protein inhibitor of activated STAT 3

ID gène: 10401

UniProt: Q9Y6X2

Pathways: Signalistation JAK/STAT