PRKAG3 anticorps (C-Term)

N° du produit ABIN8027653

Cet anticorps anti-PRKAG3 Polyclonal Lapin (ABIN8027653) détecte spécifiquement PRKAG3 dans WB. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour PRKAG3 anticorps (C-Term) (ABIN8027653)

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAG3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRKAG3 anticorps

Épitope: C-Term

Fonction: Anti-PRKAG3 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-PRKAG3 Antibody. Tested in WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human PRKAG3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PRKAG3

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Autre désignation: PRKAG3

Sujet:

Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Gene Full Name: protein kinase AMP-activated non-catalytic subunit gamma 3

Poids moléculaire: 54 kDa

ID gène: 53632

UniProt: Q9UGI9

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, L'effet Warburg