RAD51 Homolog B anticorps (AA 22-384) (Fluoro550)

N° du produit ABIN8030098

Cet anticorps anti-RAD51 Homolog B Polyclonal Lapin conjugué à Fluoro550 (ABIN8030098) détecte spécifiquement RAD51 Homolog B dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RAD51 Homolog B anticorps (AA 22-384) (Fluoro550) (ABIN8030098)

Antigène: RAD51 Homolog B (Rad51B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 Homolog B est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-RAD51 Homolog B anticorps (Fluoro550)

Épitope: AA 22-384

Fonction: Anti-RAD51L1/RAD51B Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human RAD51L1,RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1,RAD51B.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RAD51L1/RAD51B recombinant protein (Position: H22-F384). Human RAD51L1/RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1/RAD51B.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RAD51 Homolog B

Antigène: RAD51 Homolog B (Rad51B)

Autre désignation: RAD51B

Sujet:

Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

Gene Full Name: RAD51 paralog B

ID gène: 5890

UniProt: O15315

Pathways: Réparation de l'ADN