GFR anticorps (AA 164-574)
Aperçu rapide pour GFR anticorps (AA 164-574) (ABIN8030469)
Antigène
Voir toutes GFR (RAPGEF5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 164-574
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Fonction
- Anti-RAPGEF5 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human RAPGEF5 shares 95.6%,96.4% amino acid (aa) sequence identity with mouse,rat RAPGEF5,respectively.
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Attributs du produit
- Anti-RAPGEF5 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human RAPGEF5 recombinant protein (Position: E164-H574). Human RAPGEF5 shares 95.6% and 96.4% amino acid (aa) sequence identity with mouse and rat RAPGEF5, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))
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Autre désignation
- RAPGEF5
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Sujet
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Background: Rap guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the RAPGEF5 gene. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
Gene Full Name: Rap guanine nucleotide exchange factor 5
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Poids moléculaire
- 75 kDa
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ID gène
- 9771
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UniProt
- Q92565
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Pathways
- Signalisation RTK, Neurotrophin Signaling Pathway, Hepatitis C
Antigène
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