GFR anticorps (C-Term)

N° du produit ABIN1537440

Détail du produit anti-GFR anticorps

Antigène: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Épitope: AA 529-555, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFR est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.

Clone: RB36938

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RAPGEF5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur GFR

Antigène: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Autre désignation: RAPGEF5 (RAPGEF5 Produits)

Synonymes: anticorps GFR, anticorps MR-GEF, anticorps REPAC, anticorps 4932413M22, anticorps C86120, anticorps D030051B22Rik, anticorps Mrgef, anticorps mKIAA0277, anticorps mmr-gef, anticorps RGD1562891, anticorps rMR-GEF, anticorps MGC154311, anticorps Rap guanine nucleotide exchange factor 5, anticorps Rap guanine nucleotide exchange factor (GEF) 5, anticorps Rap guanine nucleotide exchange factor 5 S homeolog, anticorps RAPGEF5, anticorps Rapgef5, anticorps rapgef5.S

Sujet: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Poids moléculaire: 67733

ID gène: 9771

NCBI Accession: NP_036426

UniProt: Q92565

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, Hepatitis C