Reticulon 4 anticorps (N-Term) (Fluoro647)

N° du produit ABIN8031661

Cet anticorps anti-Reticulon 4 Polyclonal Lapin conjugué à Fluoro647 (ABIN8031661) détecte spécifiquement Reticulon 4 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Reticulon 4 anticorps (N-Term) (Fluoro647) (ABIN8031661)

Antigène: Reticulon 4 (RTN4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Reticulon 4 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Reticulon 4 anticorps (Fluoro647)

Épitope: N-Term

Fonction: Anti-Nogo A/RTN4 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Nogo A/RTN4.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Reticulon 4

Antigène: Reticulon 4 (RTN4)

Autre désignation: RTN4

Sujet:

Background: Human neurite outgrowth inhibitor (NOGO) cDNAs encodes 3 splice variants: NOGOA, NOGOB and NOGOC. The longest cDNA, designated NOGOA, has an open reading frame of 1192 amino acids. It is a potent inhibitor of neurite growth and an IN-1 antigen produced by oligodendrocytes, and may allow the generation of new reagents to enhance CNS regeneration and plasticity. Nogo-A, a member of the Reticulon family, is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The acidic amino terminus of Nogo-A is detected at the cytosolic face of cellular membranes and may contribute to inhibition of axon regeneration at sites of oligodendrocyte injury. A multivalent form of the N terminus of Nogo-A affects the morphology of both neurons and other cell types.

Gene Full Name: reticulon 4

ID gène: 57142

UniProt: Q9NQC3

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome