Serotonin Receptor 1A anticorps (C-Term) (Fluoro594)

N° du produit ABIN8036208

L’anticorps anti-Serotonin Receptor 1A Polyclonal Lapin est utilisé pour la détection de Serotonin Receptor 1A dans des échantillons de Humain et Rat. Il a été validé pour FACS.

Aperçu rapide pour Serotonin Receptor 1A anticorps (C-Term) (Fluoro594) (ABIN8036208)

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-Serotonin Receptor 1A anticorps (Fluoro594)

Épitope: C-Term

Fonction: Anti-5HT1A Receptor/HTR1A Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor, different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: HTR1A

Sujet:

Background: HTR1A (5-HYDROXYTRYPTAMINE RECEPTOR 1A), also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is a G protein-coupled receptor (GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission. HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3. The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan. Activation of 5-HT-1A receptors has been demonstrated to impair cognition, learning, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain. 5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1 (NK1) receptors and have been shown to inhibit the release of substance P, their endogenous ligand.

Gene Full Name: 5-hydroxytryptamine receptor 1A

Sequence Similarities: Belongs to the WD repeat BUB3 family.

ID gène: 3350

UniProt: P08908

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour