SOS1 anticorps (AA 177-1288) (Biotin)

N° du produit ABIN8040799

Cet anticorps anti-SOS1 Polyclonal Lapin conjugué à Biotin (ABIN8040799) détecte spécifiquement SOS1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SOS1 anticorps (AA 177-1288) (Biotin) (ABIN8040799)

Antigène: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOS1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SOS1 anticorps (Biotin)

Épitope: AA 177-1288

Fonction: Anti-SOS1 Antibody Biotin Conjugated

Homologie: Human SOS1 shares 96.5% amino acid (aa) sequence identity with mouse SOS1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SOS1 recombinant protein (Position: H177-A1288). Human SOS1 shares 96.5% amino acid (aa) sequence identity with mouse SOS1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SOS1

Antigène: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Autre désignation: SOS1

Sujet:

Background: Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene. This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.

Gene Full Name: SOS Ras/Rac guanine nucleotide exchange factor 1

ID gène: 6654

UniProt: Q07889

Pathways: Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling