XPC anticorps (AA 146-838) (APC)

N° du produit ABIN8054818

Cet anticorps anti-XPC Polyclonal Lapin conjugué à APC (ABIN8054818) détecte spécifiquement XPC dans FACS. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour XPC anticorps (AA 146-838) (APC) (ABIN8054818)

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPC est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-XPC anticorps (APC)

Épitope: AA 146-838

Fonction: Anti-XPC Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human XPC recombinant protein (Position: D146-E838).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur XPC

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Autre désignation: XPC

Sujet:

Background: Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene. The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: XPC complex subunit, DNA damage recognition and repair factor

ID gène: 7508

UniProt: Q01831

Pathways: Signalisation p53, Réparation de l'ADN