SNRPE anticorps (pSer446)

N° du produit ABIN756787

Détail du produit anti-SNRPE anticorps

Antigène: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Épitope: pSer446

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNRPE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human B-Raf around the phosphorylation site of Ser446

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SNRPE

Antigène: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Autre désignation: B-Raf (SNRPE Produits)

Synonymes: anticorps B-raf, anticorps HYPT11, anticorps SME, anticorps Sm-E, anticorps b-raf, anticorps sm-e, anticorps sme, anticorps SmE, anticorps snRNP-E, anticorps AL022645, anticorps C76690, anticorps zgc:56682, anticorps small nuclear ribonucleoprotein polypeptide E, anticorps small nuclear ribonucleoprotein polypeptide E L homeolog, anticorps small nuclear ribonucleoprotein E, anticorps SNRPE, anticorps snrpe.L, anticorps Snrpe, anticorps snrpe

Sujet:

Synonyms: B Raf phospho S446, p-B Raf phospho S446, 94 kDa B raf protein, B raf 1, B Raf proto oncogene serine threonine protein kinase, BRAF 1, Braf, BRAF1, cRmil, MGC126806, MGC138284, Murine sarcoma viral v-raf oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, p94, RAFB 1, RAFB1, v raf murine sarcoma viral oncogene homolog B1, FLJ95109.

Background: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.

ID gène: 673

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C