NRF2 anticorps (N-Term)

N° du produit ABIN8106688

Cet anticorps Lapin Polyclonal détecte spécifiquement NRF2 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NRF2 anticorps (N-Term) (ABIN8106688)

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRF2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NRF2 anticorps

Épitope: N-Term

Fonction: NFE2L2 Antibody - N-terminal region

Séquence: DILWRQDIDL GVSREVFDFS QRRKEYELEK QKKLEKERQE QLQKEQEKAF

Homologie: Cow: 86%, Dog: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 92%, Rat: 93%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2L2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38744-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NRF2

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Autre désignation: NFE2L2

Sujet:

Background Information: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Gene Name: nuclear factor, erythroid 2 like 2

Alternative Symbols: NRF2, HEBP1, Nrf-2, IMDDHH

Protein Name: nuclear factor erythroid 2-related factor 2

Poids moléculaire: 66 kDa

ID gène: 4780

NCBI Accession: NP_006155

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling