FGFR3 anticorps (pTyr760)

N° du produit ABIN8121445

Cet anticorps anti-FGFR3 Polyclonal Lapin (ABIN8121445) détecte spécifiquement FGFR3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FGFR3 anticorps (pTyr760) (ABIN8121445)

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FGFR3 anticorps

Épitope: pTyr760

Fonction: FGFR3 (Phospho Tyr760) Antibody

Specificité: This antibody detects endogenous levels of FGFR3 (Phospho-Tyr760) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human FGFR3 (Phospho-Tyr760)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FGFR3

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Autre désignation: FGFR3

Sujet:

Synonyms: Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)

Background: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys

Gene Name: FGFR3 JTK4

Protein Name: FGFR3 (Phospho-Tyr760)

ID gène: 2261

UniProt: P22607

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding